Anthelmintic Agents & Leukemia

A virus is a tiny microorganism that needs to infect other cells in order to survive. Viruses contain a few genes, stored on DNA or RNA molecules, and a few proteins. When they infect other cells, they usually damage or kill the cell.

Repurposing anthelmintic agents to eradicate resistant leukemia

For instance, anti-fungal and anti-bacterial agents as well as cardiac glycosides showed substantial anti-leukemia activity (Supplementary Fig. S1A, B). The most potent among these were the anthelmintic drugs ivermectin, moxidectin, and milbemycin, which showed up to 80% maximal cytotoxic effect compared to idarubicin (Fig. 1c).